Police were called to an industrial unit in Edwin Street, Daybrook, on Tuesday morning after illegal modifications were discovered by an energy company.
Officers searched the warehouse property and found around 1,000 cannabis plants inside.
The drugs, with a street value of hundreds of thousands of pounds, have been taken away and will later be destroyed.
A large amount of growing and electrical equipment was also put beyond use.
Nobody was present at the property and investigations are ongoing.
Sergeant Stuart Howe, of Nottinghamshire Police, said: “Cannabis grows of this nature are big business. They take a lot of time and money to set up and are often linked to violent organised crime groups.
“It is not uncommon for us to also discover slavery and human trafficking offences linked to this kind of professional drugs factory.
“That’s why we take these offences so seriously and why we will continue to pursue the criminals involved in this illicit trade.”
Anyone with additional information about this incident is asked to call 101 quoting incident 246 of 13 December 2022.
