Emergency services were called just after 7am this morning (Saturday 15 December 2018) to reports of a fire in Woodhill Road, Collingham.
Four people with serious injuries were taken from a property by Fire and Rescue crews.
The fire has been extinguished.
A section of the street is currently blocked to allow for a joint Fire and Police investigation to take place.
If you have any information call Nottinghamshire Police on 101 quoting incident number 189 of 15 December 2018.