Kyra was last seen in Chesterfield at around 12.15pm on Thursday 27 May.
The 15-year-old, who is 5ft 6ins tall and has long dark brown hair, was last seen wearing a black puffer jacket, black jeans and white Nike trainers.
It is believed she may have travelled to the city centre of Nottingham.
Anyone with any information about Kyra’s current whereabouts is asked to contact Derbyshire Police on 101 including reference 499-270521: