Police discovered a cannabis grow after attending a house to investigate reports of a burglary.
Officers were called to the semi-detached property in Radford Boulevard, Radford, by a caller who heard smashing and raised voices.
The caller then saw two men running from the address.
Officers were quickly on the scene and found a smashed window at the rear of the property.
Inside, they discovered around 100 cannabis plants across three rooms, while a fourth appeared as though it had recently been harvested.
Police are making enquiries to trace the occupants of the property.
Nottinghamshire Police’s Cannabis Dismantling Team recovered the plants and are appealing for anyone who has any information on the incident to come forward.
Inspector Richard Guy, of Nottinghamshire Police, said: “We will not tolerate the cultivation of cannabis in our communities.
“This grow appeared to be a sophisticated operation and we are pleased to have impacted on criminal behaviour by confiscating drugs before they can be sold.
“We are appealing for the public’s help in tracing two men seen running from the property towards Warner Street at around 4.20am on Monday (24 May).
“Enquiries are also well-underway to trace the occupants of the property.
“The production and selling of cannabis can sometimes be perceived a victimless crime, however, that couldn’t be further from the truth. The production and distribution of drugs has a detrimental impact on communities and ruins lives.
“Not only is cannabis growing illegal but it can also be extremely dangerous due to the fire risk, especially if people are living in adjoining properties. It can also be linked to wider crime such as potential modern slavery or county lines.
“Over the past year we have been relentless in our pursuit of these grows and the people behind them. This work will continue in the months ahead so my message to anyone involved in this illegal activity is clear: we are very likely to find out what you’re doing and, when we do, we will take decisive action.
“Anyone with any information about the grow should get in touch with us as soon as possible.”